The TULP3 Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to Tubby-like Protein 3. This antibody recognizes Human antigen. The TULP3 Antibody (C-term) has been validated for the following applications: ELISA, and Western Blot.
Description
This gene encodes a member of the tubby gene family of
bipartite transcription factors. Members of this family have been
identified in plants, vertebrates, and invertebrates, and they
share a conserved N-terminal transcription activation region and a
conserved C-terminal DNA and phosphatidylinositol-phosphate binding
region. The encoded protein binds to phosphoinositides in the
plasma membrane via its C-terminal region and probably functions as
a membrane-bound transcription regulator that translocates to the
nucleus in response to phosphoinositide hydrolysis, for instance,
induced by G-protein-coupled-receptor signaling. It plays an
important role in neuronal development and function. Two transcript
variants encoding distinct isoforms have been identified for this
gene